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activity health softly crying into a printed out stock photo of a random crowd meizitang at walmart uniontown Not surprisingly, there is an expansion of the MaSC population in p53 mice 31, which seems to be the result of altered asymmetric DNA segregation and cell division rather than the anti apoptotic activity of p53 32. Intriguingly though, inhibition of the Notch pathway in p53 mammary epithelial cells reduced the MaSC activity 32, suggesting that further research is needed to better understand the role of Notch in MaSC growth and differentiation. Finally, the p53 related protein p63, a transcription factor known to be important for stem cell function and epithelial stasis in other systems 33, 34, is also important for MaSCs..