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The contribution of factors was measured by the percentage reduction in the OR ((unadjusted OR adjusted OR) 100/(unadjusted OR 1)).17 Factors that resulted in a reduction of the OR by 10% or more were then selected for inclusion in a subsequent multivariable model (Table 5). A stepwise approach was used to construct this model, following a temporal sequence: first adolescence factors were included and then adulthood factors. The method allowed for the timing of particular events and circumstances, providing an indication of the relative and cumulative effects of particular explanations.30 The data analysis approach applied here has been used in previous studies.30, 31 Collinearity between the independent variables was explored using the technique developed by Wax32 and found results unaffected. da diet pills ‘hardball by means of chad matthews’ when tuesday