Fig. Oligonucleotide microarray profiles for (A) a single copy loss of 6.1 Mb (chr18:45,564,835 in Patient 1, (B) a single copy loss of 2.4 Mb (chr18:49,229,755 in Patient 2, (C) a single copy loss of 2.9 Mb (chr18:49,884,520 in Patient 3, (D) a single copy loss of 63 kb (chr18:51,050,140 in Patient 4, (E) a single copy loss of 101 kb (chr18:51,136,052 in Patient 5, (F) a single copy loss of 76 kb (chr18:51,059,650 in Patient 6, and (G) a single copy loss of 64 kb (chr18:51,078,120 in Patient 7. For the microarray plots, probes are ordered on the x axis according to physical mapping positions with distal 18p to the left and distal 18q to the right. , fruta planta green ohio In the present study, we recruited 26 first episode, drug nave EOS patients and 25 matched typical developing control (TDC) teenagers to investigate the characteristics of intrinsic connectivity networks (ICNs) measured using resting state fMRI. As pointed out by Kapur et al.12, “the current diagnostic system was not designed to facilitate biological differentiation and it does not”. Acknowledging the high potential that patients diagnosed based on behavioral symptoms may be highly heterogeneous in pathology, we decided against simply comparing ICNs between pre defined subject groups under the assumption that all patients share homogeneous ICN characteristics.
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