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Subsequently, concentrations of PSA were determined in the supernatants and normalized by cell numbers. Measurements were performed in quadruplicates. Shown is one representative out of two independent experiments. Key outputs of the Fellowship include a conceptual framework for internationalisation of the curriculum, a questionnaire for discipline teams to assist them to develop their own action plans for IoC, a process outline to guide academic staff embarking on the process of IoC and examples of IoC in action across a range of disciplines and universities in Australia. Matthew Cheesman, Assoc. Lecturer, School of Biomedical Sciences. fruta planta side effects The MYC oncogene is involved in many types of human cancer. The discovery of a consistent balanced chromosomal translocation involving the MYC gene in Burkitt lymphoma was the first evidence to characterize MYC as a human oncogene.1 Subsequently, MYC gene alterations have been discovered in B cell neoplasms other than Burkitt lymphoma.2 Among those neoplasms, diffuse large B cell lymphoma is the most widely studied. The presence of MYC rearrangements in patients with diffuse large B cell lymphoma treated with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R CHOP) has been shown to be associated with poor prognosis.3, 4 In particular, the so called lymphomas that are characterized by MYC rearrangement and a concurrent rearrangement of other B cell lymphoma associated genes such as BCL2 or BCL6 are associated with poor response to therapy, aggressive clinical course and dismal prognosis.5, 6, 7 These lymphomas are classified as lymphoma, unclassifiable with features intermediate between diffuse large B cell lymphoma and Burkitt lymphoma in the current 2008 WHO classification of hematopoietic neoplasms.8.
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