In the prostatic gland, expression of iNOS is already detectable in precancerous high grade prostatic intraepithelial neoplasia (Wang et al., 2003). In prostate cancer iNOS is expressed in 80 of prostate cancer specimens (Klotz et al., 1998; Aaltoma et al., 2001; Baltaci et al., 2001), showing highest expression in locally advanced and metastasized tumors (Aaltoma et al., 2001). Within the tumor, the majority of cells staining positive for iNOS are cancer cells (Klotz et al., 1998; Aaltoma et al., 2001; Baltaci et al., 2001; Wang et al., 2003; Bronte et al., 2005). – botanical slimmg It’s this lack of visibility that’s also responsible for the mega version of crowd cramping: stampedes. When we hear about stampedes, we tend to think of greed, mass panic, angry sports fans or some sort of temporary group insanity. We call a stampede death a “trampling,” as if crowds are like herds of wildebeest, willing to crush human bodies underfoot when a firecracker is set off near their hind quarters..
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