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Obesity is a complex multifactorial trait. Environmental factors favouring overweight and obesity include a high fat and energy intake, a low level of habitual physical activity as well as frequent inactive behaviours. Today, less than 50% of the children engage in routine physical activities.2, 14, 15 Concomitantly, sedentary activities (eg TV viewing) have markedly increased.2, 14, 16, 17 As many as 45% of the children snack caloric dense foods at least twice a day.2, 14, 18 These data provide some evidence for the contributions of environmental factors to overweight and obesity. fitness Lee and his colleagues has been testing parts of the Harmoni system in rats and pigs, and are moving towards trials in humans. The team uses functional magnetic resonance imaging (fMRI) during surgery to find the sometimes distant brain areas that respond to electrical pulses at the implant site. Then, by inserting chemical and electrical sensors at those sites, the researchers can put together a picture of how neurons fire and what neurotransmitters they release in response to DBS..

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