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The GCC/ genotype corresponding to higher IL 10 level may suppress IFN production and hence favors TB development. Higher stimulated IL 10 production from PBMCs in TB patients than controls is observed13, 14 and related to IL 10 1082 (A/G).14 Association of IL 10 1082 with TB was previously observed in the Cambodian20 but not in the Gambian21 and Spanish populations.14 In Table 5, the 1082 G allele frequency is found to be very low in our population compared with others. The frequency of G allele in our population (4%) was similar to that of Korean (7.4%)22 and Japanese (6.5%),23 but was significantly different from Caucasians (48%).24 The G allele frequency in Cambodians is more like that in Caucasians than in other Asian populations, however, there are significant departures from the Hardy equilibrium in both their cases and controls.20 Nevertheless, inconsistent results in association of IL 10 polymorphisms with TB may reflect ethnic specific genetic variations, or suggest the possibility that other more distal promoter elements are involved.25. planta de anacardo She says she didn’t return from the war with post traumatic stress, but she’s overwhelmed trying to piece together a new life. She and her two young children live in a tiny apartment, with so many toys scattered on the carpet that it is difficult to walk. Her husband is still in the Marines and lives near his base about two hours away.

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