1Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA2Breast Cancer Program, Cancer Institute of New Jersey, New Brunswick, NJ 08903, USACorrespondence: Yibin Kang, Tel: +1 609 258 8834; Fax: +1 609 258 2340Top of pageAbstractAdult stem cells of the mammary gland (MaSCs) are a highly dynamic population of cells that are responsible for the generation of the gland during puberty and its expansion during pregnancy. In recent years significant advances have been made in understanding how these cells are regulated during these developmentally important processes both in humans and in mice. Understanding how MaSCs are regulated is becoming a particularly important area of research, given that they may be particularly susceptible targets for transformation in breast cancer. ! s��perslim The BMI at 30 years was categorized according to the criteria recommended by WHO.23 The categories for men and women are: nonoverweight 2, preobesity (or overweight) 25 kg/m2, and obesity >30 kg/m2. Owing to the low prevalence of obesity (men 7.4% and women 3.8%), the outcome variable was dichotomized by combining preobesity and obesity together. Nonoverweight was used as a reference category.
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