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Wintertime has no shortage of outdoor activities either. Area ski resorts are opened through the winter months and when weather doesn’t cooperate, they just make their own snow. There are multiple ski resorts scattered throughout the Poconos, near Scranton, and a few miles north of Scranton near the picturesque town of Uniondale. Was Chinese teens golden swim too good to be true So why he’s changed his tone and tune this time is beyond me. MATTHEWS: E. Steven Collins, up in Philly, I remember back in the days growing up that Perle Mesta was the Dick Cheney of her day. Incubation with increasing concentrations of S nitrosocysteine, another spontaneous NO donor, as well as experiments using nuclear extracts of LNCaP prostate cancer cells yielded similar results (data not shown). In summary, these results show that NO inhibits the AR DNA binding activity in a concentration dependent manner.Prostate cells which do not express AR are less susceptible to NOEffects of NO on cell proliferation were tested with AR negative DU 145 cells as well as with AR positive LNCaP and 22Rv1 prostate cancer cells (Stone et al., 1978; Horoszewicz et al., 1983; Sramkoski et al., 1999). In contrast to LNCaP, which depend on androgenic stimuli for growth, proliferation of 22Rv1 cells is only weakly stimulated by androgens, although they are able to proliferate in the absence of androgens (Sramkoski et al., 1999; Attardi et al., 2004).