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(f) Topiramate: Topiramate is a GABA ergic anticonvulsant drug that was fortuitously found to induce weight loss in patients with epilepsy. Among obese adults, data from trials suggested the possibility of substantial weight loss (4.5 to 16.36 for topiramate versus 1.7 to 8.6 for placebo).138 Topiramate could also abrogate antipsychotic induced weight gain.139 Common adverse events include paresthesias, taste impairment and psychomotor disturbances including difficulties with concentration and sedation. A limited number of open label case series142, 143, 144 have suggested potential improvements in body weight among children with antipsychotic associated weight gain and in two extremely obese adolescent boys with Duchenne Muscular Dystrophy.145 Concerns over the impairment of cognitive function at dosages similar to those used to treat seizure disorders will likely limit its use as a stand alone agent;146 no controlled trials restricted to obese children or adolescents have been reported. li da originals The point is that as a member, you never have to worry about finding like minded others to join you there are always many friends on hand and you never know who may attend a scheduled event. The one certainty is that you will have a well organized activity or event that comes off without a hitch and stress free. All we ask of members is to bring your fun and we will do the rest..